








Semaglutide is a GLP-1 (glucagon-like-peptide-1) receptor agonist. Semaglutide works by binding to and activating the GLP-1 receptor, it stimulates insulin secretion and lowers glucagon secretion when blood glucose levels are high. It also causes a slowing down in how fast the stomach empties and signals to the brain a feeling of fulness. This results in a very powerful and lasting appetite suppression for most patients in addition to improving blood sugar levels.
It has emerged as a life-changing option for overweight or obese people who are committed to shedding a significant amount of weight and do not have other significant underlying health issues. Semaglutide is not a miracle cure or a gimmicky “fat-burning” supplement. It is a long-acting prescription medicine designed to be used over an extended period of several months or more.
Semaglutide is an FDA approved injection for the treatment of obesity. It is administered as a subcutaneous injection and is taken once per week. Semaglutide slows down the rate at which your stomach sends foods to your large intestine, which results in a longer feeling of fullness. Patients on Semaglutide have reported a reduced appetite and reduced cravings for sweets. Patients also report that overeating while on Semaglutide result in unpleasant side effects, such as nausea, which discourages poor eating habits.
Possible side effects: Nausea, vomiting, diarrhea, abdominal pain, constipation, heartburn.
Research published online 2021 Jul 7. doi: 10.3389/fendo.2021.645563
Tirzepatide is a prescription medicine used for weight loss (Zepbound brand) and type 2 diabetes (Mounjaro brand) in adults. Tirzepatide works for weight loss by decreasing appetite and slowing the movement of food from the stomach into the small intestine, which may make you feel full more quickly and for a longer period of time. In type 2 diabetes, tirzepatide decreases blood sugar levels by increasing insulin production and lowering the amount of sugar the liver makes. Tirzepatide is given as an injection under the skin once a week. Tirzepatide is a GIP and GLP-1 receptor agonist.
Tirzepatide is a GIP and GLP-1 receptor agonist, so it works (mechanism of action) by activating both GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) hormone receptors. GLP-1 helps control appetite and calorie intake, and GIP is thought to contribute to regulating food intake as well.
Common side effects: The most common tirzepatide side effects include abdominal pain, burping, constipation, diarrhea, dyspepsia, fatigue, gastroesophageal reflux disease, hair loss, hypersensitivity reactions, injection site reactions, nausea, and vomiting, which affects 5% or more patients.
Research Data https://www.drugs.com/tirzepatide.html
WARNING: Semaglutide & Tirzepatide injection(s) may increase the risk that you can develop tumors of the thyroid gland, including medullary thyroid carcinoma (MTC; a type of thyroid cancer). Tirzepatide may cause thyroid C-cell tumors. Laboratory animals who were given semaglutide developed tumors, but it is not known if this medication increases the risk of tumors in humans.
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